SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5454afc148ab753cec7cdad5e8cd030e4ad0013e2c419c317572e5b419d94afd' 
  AND token = 'gCNovrIp1WP8UaHS10e76Bhzybuqjw2Nv4/lyl9rgbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}