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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ea8c7a6fa98c755319d532e345f1f9ef1b49ee5f0db2cd8cb59f881ee81811' 
  AND token = 'hkN2eHxCnb+5Z80balAnoBagiaGrxfcy3h7iNmj3Y+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}