SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef86dc9309a27a7e486fa320c52019b7ba449b71e9ff4050b17100f45426c5b5' 
  AND token = 'uA/2EMUPbWdix/Ecq1UwXELW7jLnOE6CukLPe7xi70U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}