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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80369667123728e0bb9332c068d463ccba65411d1ce1b3a9aaa23258d74e0b38' 
  AND token = 'I9oj4OvxkZM+OGHCj48RbRTYPeVQU8kTEjMVNVHUqMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}