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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5383fad53c16f71180971a427144add605c344a7d2eb05ffb2866d0c9c6454b' 
  AND token = 'orTo74Fnuo0t/adStpwgUTYA+rUBxv1z0lrsw30rGgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}