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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724545b226ac3a7365c7a6fdd273a9182fb8f47d7c379404ceca5c4257079dd7' 
  AND token = 'qkN8SO57jtaZMbWk32qmwmqvfArY1SE6bv5wBCE11o4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}