SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aece7a1e3370e57ba4978f9c5615257e8dd643017f291d966561bf6ea002a795' 
  AND token = 'PakLhQilRVulFdJmYchqeA+W8KN11X3uou9y4nh6ZVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}