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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c38c8e3055808a09b6b299003a2d2aa274a0c1ad20d4145b71dec817ac363d' 
  AND token = 'LXDxBny9BrYsn36I323rRKMQjMw5hUS6Bf8KsmDYhW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}