SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8589795f5d063e58e9840f1ea013d05c63448375a923948d8c6eca861ade07' 
  AND token = 'XO/2rFk+sOXpbt6hL65t3/zKA/S6qZZ3HWlMzjeXLXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}