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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ae1d2ededffc6e5a70e7abd57eb2640b52b56a10366162a036f8ec84458d9b' 
  AND token = '6157veQBxh0T49Cqrex7zg1UM9ZF3vb0Bflv4hqsZ8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}