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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5641b86c8a682d09cdbc922a456130631250ed41eb1cbf3bd460200c8a437571' 
  AND token = 'c5sihNppEYe/4Y9I6WFXIr3O0kdLh6BIic8eQ+KojZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}