SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8408dc64fc7d25baac12095e86e306c099ff2491b772933ced2b2f942cb1b2bf' 
  AND token = 'SUSSQxOqS8XE5CT8B5SrcZ5iMSEj4pz6duth3Q5MjyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}