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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a669ec95b4055598eb8ee24e5b93974c7491661d73466032b15da651361734d9' 
  AND token = 'HWPy+PhqRFWOvzT2AYwtqI46NEiXr4riYP0WsiHQlUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}