SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41597679076c650caf460e92ea91c2a886b881a5c710b7af5b68bf5630b1caa8' 
  AND token = 'yqA07cW6STPI9l9bZ1EVvsX2wuhSKqAUWDubX/fyO3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}