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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290314e71b222bf4e86c1c188d581fc2274cc3f3bbd3ae88beb50f0c598f7068' 
  AND token = '4ABvGXHbI+cH7FS0f+cw3DztqRYbxBlQBBEGuPAo2qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}