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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6cae39aa307eadc8eb4e65042187bdf8d064edfeebb7a2c39d32fdab4756c33' 
  AND token = 'M36bZ1QyNyUF6hf7jokfLrDSxkoP1j0lfI4oKjszc9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}