SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74fb8c4672c49abbea89ad13057fcee5a33a8df2bf9d15407032e04f14561351' 
  AND token = 'OYxvXd9f7SMcz/1j5PnARtfNTS3mABag37Jijy3PEhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}