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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a525fe5a12ca25b9c64f4bc47d6e27fa7e42192b74538d81e45b0581df1b11' 
  AND token = 'q62/JzkntjqyKd4PdBeIoL3uI59Wn6QJ6B1wKAcvZpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}