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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1288e9da5fa89399b1bb8f13e38a4f51c9c78686ebac13055f1f0be224f314d' 
  AND token = 'IyEnNsMz1mxvuNSD07c9C3b+1OVkeoXJc0RRORP9Itk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}