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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cef9dee242b7061626dcbc1bfd5b94a56bbb472cde600d0f2fc856ecd8ce038' 
  AND token = 'BikGUMYQnS5UBfazoYzp1fEGxTWI+nDBTITIW/rhCOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}