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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41a8ca0c05f2b5e87456fac5821d249b1d8778f538b473d8dd4517988073550' 
  AND token = 'Z0fl22nkrDiQ6V2CgX8VNfgrVM4I+A9yCKVkQOW0AMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}