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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89a2741dbf809c9ecd014633a69e8f514a1575a507c847107d923e6ab58e3e84' 
  AND token = '4jv0opN1qu0SPca//UJ8tKAo4UbppG8ioBYm9wkeMMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}