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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d887a306f3250ae354d5ee45ca98d1270011ca346f4de41bf51e424afc56c6' 
  AND token = 'XeOkCcyzXrPfxsC8vBjB1ChjqiY1kC3MHzp/j1zALgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}