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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7422f62bff3d1d3825f935e8b447281574aaa8f024301a494718395b9dccc6' 
  AND token = 'PD5T9Gfnqrs6sz9OnDU060Ltfv0fIPMtv5GkTR3mPKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}