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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869b48a51b7afc13ac96c6ddbaf12d0c63a4e6a25299a1d98147ebbb53354e23' 
  AND token = 'HSrHeAQNt3/rJGl9krj78rN9VDjSjBnM90ySUWePlx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}