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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00088b5d7185328caa10791a2739d7e543785119aecd003c96c14843e6e2dc11' 
  AND token = 'aT8Yp0HZI09gbLXxYWlaczk9wlZysFqfIkUy/0UeuxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}