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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c61a067c46aa541485b1fbf2c696e15c97f1c076bd6f2c7edaeb1e3a9144625' 
  AND token = 'uygWZSA464HtVVzLEBr2nBXGHf8W4I2uaslFQY1fNVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}