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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6abe75a1cea74447263a3874ce196399b7d0f0cc89e773d4d8a2f9b42a2738f' 
  AND token = 'k5Hu0UBwnKTJ2MNE6JHbGVm3fSXia+bCAlaPFskMum0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}