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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c88fbc2e3a5d76f8ec1d52e0adfccb99d3a026d885729d89130ef3355469194' 
  AND token = 'wZgmPCXRQ80z2qAf0jyk+G2OduC6KVQRWoWCYFbefR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}