SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0ea849d12c0a051ac220509b8c112134b69ea90c28f1e97e484c06f6d0ca71' 
  AND token = '7NQLofjUuZFJbNMrKSwo8UMXmFrmRMB6Drayi7aMNSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}