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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7f42b763cc4b189bedbf500461f6e5ea2fac8eda13ffd459db93f809f6eb1e' 
  AND token = 'TKt3Rr0Jo3QCE+8DVWl+lf2PBLQrxUqcY3WibG4YvE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}