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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8cf81bac7af82caf42755b389dbe55fd85ea0456cfdc3e2fe423af56d1891da' 
  AND token = 'sXgGNWe5X8DjiWfbqsAnzKnw5PC4e+Wo8mM7yLHsy/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}