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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1321ff1991d5d4c0b10724154aa1f5c376f2150a38d8844d688863d7b1add9' 
  AND token = 'poo61UH1drkGK13J7oSs7d8UiY1F0gNwSyAJbLud/VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}