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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6768adc1fc4d35258077d96a6af6755a7a8b521b11d8521c6358a21f88fcf0' 
  AND token = '+bjqLo6JPebDjr5B0cdM+RNnE2yq+hdW0YHna1bVz3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}