SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191432527d026c498de7c428cb59f6e8ec6f3f255e89db65afe483b83b528c76' 
  AND token = 'xjuxQLELM9eH2a2ZZN78cWDuusZ6PVws69uZds6/XSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}