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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a66964db1f885d326685602ab5d4e09acaa8b76300033faea56a901fd2594b' 
  AND token = 'DKtC10pEtqO8e0FeNjiKE+SXm5XzAFh8+oo1DLsFuVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}