SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053f4cbeb14551b3d31438e0ca0253820e0c577f8abcd11d05cebfa0a6114dfa' 
  AND token = 'Sw0800oVSzYdc2gzowmNdsWwJ6fKzRoWk4AF45Z6gV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}