SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5cd6936d7231e6f397a6f2e80e7b6b1e659f7f8952c040d23cb6a2daa93eaf' 
  AND token = 'F1L1TypZrwrnxj3b/EvddMKn59yLe7SlAY6uQ9+BGhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}