SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2bba2d289b89c5f5bba9bd2cb441473b9f3394ffc3ccda3464e29827e66a952' 
  AND token = 'Jjv+B+M6iadtCUt3yqdWun0LyftHFCv7fgSIAv0Jp3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}