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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25d0753a5f4434f6e526d9d4f65250416f166e3f72182e68659f474e5343ccd' 
  AND token = '3ArmSU7D0rRK4ehPKmUdi23FyLQ1zZVXTf5TOYBxDTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}