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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75f9f124198d3e9b86082769f4c7098d07322a8dde0ed21a477fa77ab252c8e' 
  AND token = 'H0R2uCmEqY2vuICOPsEDnGe9nHsu3JLLbt1NEBrAsV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}