SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd08d5f82156d76dbcc56988dd47b774fcb3d166c8a510bb89b35529d46e1bbe6' 
  AND token = 'eXGHDTaKsnXedJhcfExhmi8Rm8I/Sw6VCIEvyNngzoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}