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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1044dbd76d8868205de50d43b921b6d8b8e28b1f7bb24954c9bf7b5158c688f0' 
  AND token = 'vFRK4rOURbXcYkx48aYnTqH7xKYSVfc+JqB5Dqv6qiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}