SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf264e05d92d5cbb97e21b84ec8425f70bcc34180b09ddc42778da06013ee44' 
  AND token = 'hNJxsmsNKb+h9fF89FSHcXc88eBvgl1FLcWilQqTEss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}