SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd8f45833424505be7cc069b919a9396143ab236172e6a80f9feee7901646848' 
  AND token = 'UF/fv3Hpd9yh6YfN9ODBNRagsLZovxkwZeDE4Vw2tsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}