SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7868089771dbfd185bd0928d8fb2d6bd5d93874dfb385d527961a585b894652' 
  AND token = 'BIkbIBfTYde8Va+DmxfXjXAJVzkpJJ0de+vcgxaEUAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}