SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dfa409921b9b653aaeb6569c6ff810ad14e5f35441ad07d56fa33843336a830' 
  AND token = 'tDbhbhS3A+m9X0i1MxLcDP7gh7dsT3D46wlvfFnprOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}