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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18010870957e0d9436086fd1c625ed8d8fd48446cb5ab5d672b219ad7907ace6' 
  AND token = 'U/DlLW3xoa7JVrfPXA1v5fAzY5a3QLXeLLwwiQ8MvSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}