SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d85352cca62b44b0f541f9f2528e0bea32f05801579f64dbacd61f9d08f81a3' 
  AND token = 'sw/AbOkyNsNFO2d0rXmRRVwb5n/qEYe1FEYi6G9rAxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}