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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817d1fb0e289644aa85dff2456d5e53a18bae0b30a5d75919c657fe343f930d2' 
  AND token = '+qU5DkWb3RmFgbgArEbmKVPtFYZkIUj0OSU+tQdyxv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}